Results A total of 386 258 individuals (mean age, 56 years 52.3% female) were assessed. Main Outcomes and Measures Any cardiac arrhythmia, including atrial fibrillation or flutter, supraventricular tachycardia, ventricular tachycardia, premature atrial complexes, and premature ventricular complexes. After exclusion criteria were applied, 386 258 individuals were available for analyses.Įxposures Daily coffee intake and genetic polymorphisms that affect caffeine metabolism. Objective To assess the association between consumption of common caffeinated products and the risk of arrhythmias.ĭesign, Setting, and Participants This prospective cohort study analyzed longitudinal data from the UK Biobank between January 1, 2006, and December 31, 2018. However, evidence that the consumption of caffeinated products increases the risk of arrhythmias remains poorly substantiated. Importance The notion that caffeine increases the risk of cardiac arrhythmias is common.
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